Mike Dawson (JAMIE FOXX) and his fiancée, Rae (NIA LONG), are taking a vacation from their busy lives in Chicago with a romantic getaway to the Grand Canyon. That's short-lived, however, for when Rae discovers that he spent their home savings on a vintage car, she dumps him at the "Sip & Zip" convenience store where they stopped for a bathroom break, and catches a ride to the Las Vegas airport.
Determined to win her back, Mike immediately runs into problems when his car his stolen. Heading into the convenience store to call the police, Mike meets the store's manager/clerk, Jack (JOHN CULLEM), along with Rusty (SAM GIFALDI), a video game junkie who thinks he's Puff Daddy; Clarence, an all-knowing philosophy spouting biker; and Mary (SARAH PAULSON), a somewhat shy woman who knows her man is cheating on her.
With Deputy Beaumont (JAKE BUSEY) on the way, Mike thinks that he might have a chance to get to Vegas before Rae catches her plane, but that's before Rodrigo (EDUARDO YANEZ), and his two bumbling associates, Trina (ROSELYN SANCHEZ) and Sal (DIEGO FUENTES), enter the store, prepared to rob it. When the deputy finally arrives and gets suspicious of what's occurring in the Sip & Zip, he calls Sheriff Pembry (BARRY CORBIN) who shows up with an entourage of armed, but not altogether brilliant locals.
Not surprisingly, Trina and Sal take off, leaving Rodrigo with a small number of hostages, the most perturbed being Mike who realizes he's running out of time. As the locals show up to gawk at the event and the press arrives to cover it live, Rae sits in an airport bar, drowning her sorrows with bartender
Gloria (JULIE HAGERTY), hoping that Mike will show and make up with her.
That begins to seem increasingly unlikely as even more people show up at the convenience store, including a Vegas S.W.A.T. team that awaits orders from Sheriff Pembry to move in. Realizing that he's surrounded by idiots on both sides of the situation, Mike does what he can to resolve the crisis so that he can get to Vegas and stop Rae before she boards her plane back home.