It's the 21st century, and as a result of overpopulation and unchecked pollution, mankind has ecologically laid waste to Earth. As a result, the decision to colonize Mars has been made and for the past twenty years, the unmanned Mars Terraforming Project has been in place with oxygen-producing algae generating what will become a breathable atmosphere capable of sustaining life.
Unfortunately, the oxygen levels have recently taken a downturn, so the first manned mission to Mars has been sent off to discover why. Led by Bowman (CARRIE-ANNE MOSS), the pilot and mission commander, the six-month journey takes her and her crew -- Chantilas (TERENCE STAMP), the chief science officer; Santen (BENJAMIN BRATT) the egotistical, hotheaded copilot; Burchenal (TOM SIZEMORE) one of the world's leading bioengineers; Pettengil (SIMON BAKER) a terraforming expert and a last minute replacement on the ship; and Gallagher (VAL KILMER) the mechanical systems engineer -- to the red planet.
When the remnants of a solar flare incapacitate their mother ship, Bowman sends the rest of the crew to the planet while she remains onboard, hoping to repair the ship and thus resurrect their only way home. Crashing on the planet, the landing crew then sets out to discover what's gone wrong on Mars. As they do so, they must contend with an inhospitable environment, unexpected discoveries, and AMEE, the multi-tasking Autonomous Mapping Exploration and Evasion robot on loan from the Marines that's reverted to its self-preserving military mode and thus sees the crew as the enemy it must destroy.