Samuel Berg (MAX VON SYDOW) is the owner of a lucrative but remote casino whose string of luck extends back to being the sole survivor of a concentration camp. In the bowels of his gambling establishment, he runs an underground, but high-stakes game of luck where he's yet to lose. Those who do, however, not only forfeit possession of those they "own" - signified by photos of those people - but also their lives.
Federico (EUSEBIO PONCELA) is Samuel's protégé with the ability to remove anyone's luck via a simple touch of the hand, a measure that comes in handy when an unknowing gambler hits a winning streak. When he wants to break free of Samuel, however, the master uses the same tactic on him, thus rendering him powerless.
Years later, Federico is still searching for a recruit that he can use to do battle with Samuel. He thinks he's found that person in Tomas Sanz (LEONARDO SBARAGLIA), the sole survivor of a major airline crash. Discovered with stolen money taped to his body, Tomas is put under police custody at a hospital, but Federico manages to get him out.
He then introduces him to the secret world of high-stakes luck games and puts him into various elimination round challenges against other lucky opponents, such as Alejandro (ANTONIO DECHENT) the bullfighter, to determine who will next battle Samuel. At the same time, local cop and fellow lucky survivor, Sara (MONICA LOPEZ), is hot on the trail of those behind such contests, while Tomas' girlfriend, Ana (PAZ GÓMEZ), is also under watch.
Facing various games of luck and the threat of losing Ana to one of the winners, Tomas sets out to battle Samuel and find out who's the luckiest man alive.