Delia (KYRA SEDGWICK) is a woman who once used sex as power over various males, but is now married to Kurt Wurtzle (DAVID WARSHOFSKY) with three kids. When Kurt severely beats her in front of the kids - much like her father, Pete Shunt (BRIAN TARANTINA), did with her mother - she hits the road.
After staying in a shelter, she calls up a former high school classmate, Fay (MARA HOBEL), and asks if she and her kids can stay with her and her husband, Greg (CHRISTOPHER FITZGERALD), for a while. She eventually gets a job waiting tables where she must put up with the leering flirtatiousness of Mylert (LEO FITZPATRICK), the short order cook's son.
Greta (PARKER POSEY) is a cookbook editor for a publishing house where her boss, Mr. Gelb (WALLACE SHAWN), has just informed her that author Thavi Matola (JOEL DE LA FUENTE) wants her to edit his book. She's excited about that and reportedly tells her husband, Lee (TIM GUINEE), that Thavi is gay to allay any potential suspicion.
Coming from a broken family - her father, Avram (RON LEIBMAN), left her mother, Maroushka (KALUSKA POVENTUD) - Greta has a problem with fidelity. Not only does she fool around with Thavi and Max (BEN SHENKMAN), a guy she met in a coffee shop, but she also had an affair with her former boyfriend, Oscar (JOSH PHILIP WEINSTEIN), right before her wedding to Lee.
Paula (FAIRUZA BALK) is a troubled young woman and former runaway. Not only has she recently found out she's pregnant by her live-in boyfriend, Vincent (SETH GILLIAM), but she's also just left the scene of a horrible accident that killed a man she just met. Although she hasn't spoken to her mother, Celia (PATTI D'ARBANVILLE), in years due to her new boyfriend, Peter (DAVID PATRICK KELLY), Paula heads there to see her. Along the way, she picks up a teenage hitchhiker, Kevin (LOU TAYLOR PUCCI), who appears to have been tortured and tries to help him.