Carolyn McDuffy (CHRISTINA RICCI) is a senior at Southern California State University who loves her sorority, Alpha Omega Pi. A bright and bubbly young woman, Carolyn's life has been both easy and happy, much like her elitist mother, Chippy (LISA BANES).
Yet, when sorority president Julie Thurber (MARISA COUGHLAN) - in her quest to outdo a rival house for Sorority of the Year honors - decides they should help train some mentally and physically handicapped athletes for the Challenged Games, Carolyn and her roommate, Jeanine Kryszinsky (DOMINIQUE SWAIN), raise their voices in protest.
Despite their belief that such people aren't "right" and don't convey the image the sorority should project, the two girls - along with the rest of the sorority sisters - are each assigned their own athlete to help. Carolyn's is Pumpkin Romanoff (HANK HARRIS), a young man in a wheelchair who's so taken with her that he can only repeat her name. This, of course, freaks her out.
Her boyfriend, university tennis star Kent Woodlands (SAM BALL), thinks she's making too much out of nothing and adds that such people are just like them beyond God choosing to make them a little different. Carolyn reluctantly continues with the training, but then seems to be off in a different world in both her sorority functions as well as in class, such as with poetry professor Robert Meary (HARRY J. LENNIX).
This is because she now sees that the world isn't perfect and thus she's ready to quit on Pumpkin when he states that she's his friend and says that she's beautiful inside. Carolyn's view of him suddenly changes, and she even tries to set him up with her dateless friend, Cici Pinkus (MELISSA McCARTHY). When that goes disastrously wrong, Carolyn finds herself drawn even closer to Pumpkin, much to the dismay of Kent, her sorority sisters and the boy's overprotective mother, Judy (BRENDA BLETHYN).
From that point on, and as Carolyn's life is turned upside down due to her actions, self-discovery and newfound love for Pumpkin, whose condition improves due to her interest in him, she must decide what's right for her in life.