Greg (WILL SANDERSON), his girlfriend Cynthia (SONYA SALOMAA) and their friends Simon (TYRON LEITSO), Alicia (ONA GRAUER) and Karma (ENUKA OKUMA) are hoping to attend the rave party of the year on a remote island off the coast of Seattle. They miss the boat there, however, and end up chartering another boat through seasoned Captain Kirk (JUERGEN PROCHNOW) who agrees to ferry them once the price is right.
Salish (CLINT HOWARD), his first-mate, however, warns that they shouldn't do that as the Isla del Morte literally translates as the Island of Death. The college students don't care and pay Kirk some extra cash to elude Coast Guard official Casper (ELLIE CORNELL) so that they can get to the party on time. He does, but she follows him, suspicious of his actions and possible cargo.
The captain eventually deposits them on the island where he hopes to stash his goods before Casper arrives. The students, however, discover that the party area is deserted, a fact that doesn't sit well with Alicia. Her suspicions are soon realized as some in their group meet a grisly demise at the hands of what appear to be zombies.
They eventually run into the few party survivors, including Rudy (JONATHAN CHERRY), Liberty (KIRA CLAVELL) and Hugh (MICHAEL EKLUND), and fight alongside Kirk and Casper to get to the island's lone house that might provide them some security. As the zombies, led by the immoral Castillo (DAVID PALFFY), continue their deadly attacks on the humans, the survivors do what they can to avoid them and figure out what's happening.