It's spring break in Cancun, Mexico and various young people have arrived for eight days and nights of partying. Among them are 21-year-old Sara and her new friend Matt, who bond over a jellyfish incident. 18-year-old Alan is from Texas and has never had a drink, but that's sure to change. Identical twins Nicole and Roxanne aren't anywhere as inhibited and perform in a dual wet T-shirt contest.
21-year-old Paul is drawn to community college student Sky, while his friend Jorell enjoys hanging out with Alan and Jeremy, a 22-year-old business-marketing graduate who's similarly enticed by the hordes of scantily clad women surrounding them, such as 20-year-old Laura.
Then there are friends Heidi and David who've never "hooked up," 25-year-old model Casey, biochemistry major Brittany, 20-year-old management major Ben, and sex columnist Amber. As the week of partying wears on, they and the rest of the revelers pursue their various goals of sun, fun, sex, drinking and more.